Global Mycoplasma Testing Market is slated to see a lucrative growth rate of 11% by 2027

Mycoplasmas are the smallest known free-living microorganisms and are frequent contaminants of mammalian cell cultures. For the safety and purity of vaccines and other biological cell-derived products, it is crucial that the cell substrates and unprocessed bulk materials are free of adventitious agents, including mycoplasma. 

In many cases, mycoplasmas vary from other forms of bacteria, making them difficult to culture and identify. Testing is done to detect mycoplasma like Mycoplasma hominis, Mycoplasma genitalium, Mycoplasma pneumoniae, and Ureaplasma urealyticum which can cause nongonococcal urethritis (NGU), prostate inflammation (prostatitis), vaginal discharge, and pelvic inflammatory disease (PID) in both men and women.

Rising Concerns of Cell Culture Contamination to Trigger the Growth of the Global Mycoplasma Testing Market

Mycoplasmas randomly contaminate the fluids used in the bioprocessing and cell culture. It is commonly known that primary cell cultures have a minimum contamination rate of 1% and continuous cell cultures have a contamination rate of between 15% and 35% due to mycoplasma. Ineffective culturing methods or old laboratory apparatus can result in mycoplasma contamination. Reusing pipet tips is an example of poor culture method which might spread the contaminant by transferring mycoplasma-infected media into sterile media. Further, a faulty laminar flow might spread mycoplasma-carrying dust and aerosols throughout a biosafety cabinet, contaminating all the medium and cells within. 

The mycoplasmas mainly enter the cell culture through many difficulties to trace sources. These include healthcare workers in the lab, serum, material used in cell culture, water baths, incubators. Among the mentioned sources, contamination by patients accounts for the highest share. The contaminants can be transmitted through dirty clothes, lab gear, people speaking extremely close to a laminar airflow, the scalp, sneezing, coughing, etc. Also, wherever the cell cultures are kept, a steady inflow of people will raise the possibility of contamination. Out of over 190 total species of mycoplasma, only 20 distinct mycoplasma species of human, bovine, and porcine origin have been found in cell culture. Eight of the species account for nearly 95% of all mycoplasma contamination in cell culture. These includes M. arginini (bovine), M. fermentans (human), M. hominis (human), M. hyorhinis (porcine), M. orale (human), M. pirum (human), M. salivarium (human), and Acholeplasma laidlawii (bovine).

Regular testing is the best protection method against mycoplasma contamination which can identify the contaminated cultures and reagents. In the case of batch adulteration or a product recall, contamination of cell substrates used in the development of biopharmaceuticals constitutes a major economic risk for manufacturers as well as a safety concern for patients. Regular mycoplasma testing is essential to be performed during the product manufacturing and development phase to prevent these risks.

Aggressive Strategies Followed by the Established Market Players and Laboratories in the Global Mycoplasma Testing Market

Rapid innovations and developments in the mycoplasma detection have enabled the leading market players to develop an innovative, advanced, quick, and an easy-to-use tests. Such innovations tend to offer a comprehensive edge to all the manufacturers and thus, market players are emphasizing on growing their investments for new product development and enhancing their regional reach to boost their current position in the global mycoplasma testing market. 

Inspite of the emerging challenges in the global mycoplasma testing market such as long turnaround time, quality control issues, lengthy analytical and lead time, etc. the global mycoplasma testing market has a great potential to grow at a healthy rate and is slated to witness a consistent momentum in the coming years due to a major focus on technological advancements, wider and global acceptance in biopharmaceutical manufacturers, and rapid developments of rapid mycoplasma testing by leading market players in the mycoplasma testing market. 

Competitive Landscape Analysis: Mycoplasma Testing Market

The global mycoplasma testing market is marked by the presence of some of the leading market players such as Thermo Fisher Scientific; Charles River Laboratories International; Merck KGaA; Lonza Group; PromoCell GmbH; American Type Culture Collection.

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