Global Single-Use Bioreactors Market valued at $3.39 billion in 2021, is poised to witness a Healthy Growth of 20% in the next 5 Years : MediTech Insights

Single-use bioreactors are bioreactors that use the disposable bag as a substitute for a culture vessel made of stainless steel or glass. It is widely used by pharmaceutical companies for cell harvesting, media & buffer preparation, filtration, purification, and virus inactivation.

Due to their Ability to Enhance Flexibility, Reduce Investment & Limit Operational Costs, Single-use Bioreactors Have Become Established in Modern Biopharmaceutical Processes

Enhanced flexibility is one of the biggest benefits of single-use bioreactors. There is a growing trend towards multi-drug facilities, which warrants the production of different drugs using the same facility with minimum time & cost and top-notch quality. In such scenarios, one of the key manufacturing challenges is line clearance and validation of cleaning to ensure there is no carry-over from earlier batches. Downtime limits the number of batches produced in a given period.

Single-use bioreactors significantly reduce the time spent preparing the bioreactor for the subsequent batch. A line changeover with a stainless-steel bioreactor can take ~6 to 10 hours and three weeks for a full product changeover while by using single-use bioreactors it is likely to take 2 hours for line changeover. If the manufacturing line is composed of all single-use components such as bags, filters, and connectors, the total time for product changeover can be 48 hours. Single-use bioreactors possess the capability to reduce downtime from two to three weeks to 48 hours, which in turn can significantly impact a company’s output.

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Key Advantages of using Single-Use Bioreactors are as follows:

  • Elimination of validation issues as no cleaning process is required
  • Lowers the risk of cross-contamination
  • Reduces operating costs and capital investments (including space, labour requirements, and utilities)
  • Single-use bags are scalable and can be adjusted to different volumes
  • Simple installation

Potential Time Savings for Highly Trained Personnel : Another Key Benefit of Single-use Bioreactors

Generally, drug development research, process development, and scale-up activities are performed by highly qualified and trained personnel. These individuals are involved in every stage of a study from early-stage research through to benchtop manufacturing. With stainless steel or glass benchtop bioreactors, individual components need to be cleaned, assembled, leak-tested, sterilized, and cooled before every trial batch is taken. However, the use of single-use bioreactors almost eliminates these steps, which allows scientists more time to focus on their developmental studies.

Competitive Landscape Analysis : Single-use Bioreactors Market

Some of the key players operating in the Global Single-use Bioreactors market are Sartorius Stedim Biotech, Thermo Fisher Scientific, Danaher Corporation, and Merck KGaA.

Other Players Operating in the Single-use Bioreactors Market are as follows:

  • ABEC
  • Cellexus
  • Celltainer Biotech BV
  • Distek Inc.
  • G&G Technologies Inc.
  • GPC Bio, among others

Explore More Insights on Single-Use Bioreactors Market @ https://www.marketwatch.com/press-release/global-single-use-bioreactors-market-valued-at-339-billion-2021-is-set-to-witness-a-healthy-growth-rate-of-20-in-the-next-5-years-2021-10-29

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